Lablog4-11：Fragmentation of angiotensin-I converting enzyme inhibitory peptides from bonito meat under intestinal digestion conditions and their characterization

  • 投稿日
  • 著者 bioaffinity
  • 対象DB Lablog4
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Authors

Fida MD Hasan, Yoichi Kumada, Naoto Hashimoto, Tomohisa Katsuda, Masaaki Terashima, Shigeo Katoh

First author

Fida Hasan

Corresponding author

Shigeo Katoh

Publication Style

Journal name Food and Bioproducts Processing

Year　　

Volume, issue, pages

84(2 C) 135-138

Abstract

Kinetics of fragmentation of angiotensin-I converting enzyme inhibitory peptides obtained by digestion in gastric juice were studied under intestinal digestion conditions and their inhibitory activities were determined. A fragment IKYGD produced by digestion, as well as IKWGD synthesized, showed similar inhibitory activity to the original peptides. These peptides somehow were resistant to tryptic and/or chymotryptic digestion, and IK + aromatic amino acid might be important functional parts in some kinds of ACE inhibitory peptides.

DOI https://doi.org/10.1205/fbp.05152